Visible light-activated biocompatible photo-CORM for CO-release with colorimetric and fluorometric dual turn-on response

J. Liu; P. Hoffmann; J. Steinmetzer; S.H.C. Askes; S. Kupfer; H. Görls; S. Gräfe; U. Neugebauer; U.R. Gandra; A. Schiller

doi:10.1016/j.poly.2019.04.031

Visible light-activated biocompatible photo-CORM for CO-release with colorimetric and fluorometric dual turn-on response

J. Liu, P. Hoffmann, J. Steinmetzer, S.H.C. Askes, S. Kupfer, H. Görls, S. Gräfe, U. Neugebauer, U.R. Gandra, A. Schiller

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

© 2019We introduce a colorimetric as well as fluorometric dual response CO-releasing molecule as Mn(I) tricarbonyl complex with a nitrobenzoxadiazole (NBD) fluorophore. DFT and TD-DFT studies corroborate that extended conjugation in the principal ligand frame will help to release CO at low energy radiation. A very low toxicity of NBD-CORM was observed against LX-2 and HepaRG® human cell lines.

Original language	English
Pages (from-to)	175-181
Journal	Polyhedron
Volume	172
DOIs	https://doi.org/10.1016/j.poly.2019.04.031
Publication status	Published - 1 Nov 2019
Externally published	Yes

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10.1016/j.poly.2019.04.031

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title = "Visible light-activated biocompatible photo-CORM for CO-release with colorimetric and fluorometric dual turn-on response",

abstract = "{\textcopyright} 2019We introduce a colorimetric as well as fluorometric dual response CO-releasing molecule as Mn(I) tricarbonyl complex with a nitrobenzoxadiazole (NBD) fluorophore. DFT and TD-DFT studies corroborate that extended conjugation in the principal ligand frame will help to release CO at low energy radiation. A very low toxicity of NBD-CORM was observed against LX-2 and HepaRG{\textregistered} human cell lines.",

author = "J. Liu and P. Hoffmann and J. Steinmetzer and S.H.C. Askes and S. Kupfer and H. G{\"o}rls and S. Gr{\"a}fe and U. Neugebauer and U.R. Gandra and A. Schiller",

year = "2019",

month = nov,

day = "1",

doi = "10.1016/j.poly.2019.04.031",

language = "English",

volume = "172",

pages = "175--181",

journal = "Polyhedron",

issn = "0277-5387",

publisher = "Elsevier Ltd",

}

Visible light-activated biocompatible photo-CORM for CO-release with colorimetric and fluorometric dual turn-on response. / Liu, J.; Hoffmann, P.; Steinmetzer, J.; Askes, S.H.C.; Kupfer, S.; Görls, H.; Gräfe, S.; Neugebauer, U.; Gandra, U.R.; Schiller, A.

In: Polyhedron, Vol. 172, 01.11.2019, p. 175-181.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - Visible light-activated biocompatible photo-CORM for CO-release with colorimetric and fluorometric dual turn-on response

AU - Liu, J.

AU - Hoffmann, P.

AU - Steinmetzer, J.

AU - Askes, S.H.C.

AU - Kupfer, S.

AU - Görls, H.

AU - Gräfe, S.

AU - Neugebauer, U.

AU - Gandra, U.R.

AU - Schiller, A.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - © 2019We introduce a colorimetric as well as fluorometric dual response CO-releasing molecule as Mn(I) tricarbonyl complex with a nitrobenzoxadiazole (NBD) fluorophore. DFT and TD-DFT studies corroborate that extended conjugation in the principal ligand frame will help to release CO at low energy radiation. A very low toxicity of NBD-CORM was observed against LX-2 and HepaRG® human cell lines.

AB - © 2019We introduce a colorimetric as well as fluorometric dual response CO-releasing molecule as Mn(I) tricarbonyl complex with a nitrobenzoxadiazole (NBD) fluorophore. DFT and TD-DFT studies corroborate that extended conjugation in the principal ligand frame will help to release CO at low energy radiation. A very low toxicity of NBD-CORM was observed against LX-2 and HepaRG® human cell lines.

U2 - 10.1016/j.poly.2019.04.031

DO - 10.1016/j.poly.2019.04.031

M3 - Article

VL - 172

SP - 175

EP - 181

JO - Polyhedron

JF - Polyhedron

SN - 0277-5387

ER -

Visible light-activated biocompatible photo-CORM for CO-release with colorimetric and fluorometric dual turn-on response

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