Visible light-activated biocompatible photo-CORM for CO-release with colorimetric and fluorometric dual turn-on response

J. Liu, P. Hoffmann, J. Steinmetzer, S.H.C. Askes, S. Kupfer, H. Görls, S. Gräfe, U. Neugebauer, U.R. Gandra, A. Schiller

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

© 2019We introduce a colorimetric as well as fluorometric dual response CO-releasing molecule as Mn(I) tricarbonyl complex with a nitrobenzoxadiazole (NBD) fluorophore. DFT and TD-DFT studies corroborate that extended conjugation in the principal ligand frame will help to release CO at low energy radiation. A very low toxicity of NBD-CORM was observed against LX-2 and HepaRG® human cell lines.
Original languageEnglish
Pages (from-to)175-181
JournalPolyhedron
Volume172
DOIs
Publication statusPublished - 1 Nov 2019
Externally publishedYes

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