Abstract
Background: Depressive symptoms and decreased physical functioning are interrelated conditions and common in older persons, causing significant individual and societal burden. Evidence suggests that Vitamin D supplementation may be beneficial for both mental and physical functioning. However, previous randomized controlled trials have yielded inconsistent results and often had suboptimal designs. This study examines the effect of Vitamin D supplementation on both depressive symptoms and physical functioning in a high-risk population of older persons with low Vitamin D status. Methods/design: The D-Vitaal study is a randomized, double-blind, placebo-controlled trial investigating the effects of a daily dose of 1200 IU Vitamin D
Original language | English |
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Article number | 151 |
Journal | BMC Geriatrics |
Volume | 15 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2015 |