%PDF-1.7
%
1 0 obj
<<
/AcroForm 2 0 R
/Metadata 3 0 R
/Names 4 0 R
/OCProperties <<
/D <<
/OFF []
/Order [5 0 R]
/RBGroups []
>>
/OCGs [5 0 R]
>>
/OpenAction [6 0 R /FitH 804]
/Outlines 7 0 R
/PageLabels <<
/Nums [0 8 0 R]
>>
/PageMode /UseOutlines
/Pages 9 0 R
/SaveStreams <<
/Q 10 0 R
/q 11 0 R
>>
/Type /Catalog
>>
endobj
12 0 obj
<<
/Author (Eirini Karyotaki)
/CreationDate (D:20180702153049Z)
/Creator (Elsevier)
/CrossMarkDomains#5B1#5D (elsevier.com)
/CrossMarkDomains#5B2#5D (sciencedirect.com)
/CrossmarkDomainExclusive (true)
/CrossmarkMajorVersionDate (2010-04-23)
/ElsevierWebPDFSpecifications (6.5)
/Keywords (Internet-based guided self-help; Psychotherapy; Depression; Meta-analysis; )
/ModDate (D:20200716152344+02'00')
/Subject (Clinical Psychology Review, 63 \(2018\) 80-92. doi:10.1016/j.cpr.2018.06.007)
/Title (Do guided internet-based interventions result in clinically relevant changes for patients with depression? An individual participant data meta-analysis)
/doi (10.1016/j.cpr.2018.06.007)
/robots (noindex)
>>
endobj
2 0 obj
<<
/DA (/Helv 0 Tf 0 g )
/DR <<
/Encoding <<
/PDFDocEncoding 13 0 R
>>
/Font <<
/Helv 14 0 R
/ZaDb 15 0 R
>>
>>
/Fields []
>>
endobj
3 0 obj
<<
/Length 8618
/Subtype /XML
/Type /Metadata
>>
stream
application/pdf
doi:10.1016/j.cpr.2018.06.007
Do guided internet-based interventions result in clinically relevant changes for patients with depression? An individual participant data meta-analysis
Eirini Karyotaki
David Daniel Ebert
Liesje Donkin
Heleen Riper
Jos Twisk
Simone Burger
Alexander Rozental
Alfred Lange
Alishia D. Williams
Anna Carlotta Zarski
Anna Geraedts
Annemieke van Straten
Annet Kleiboer
Björn Meyer
Burçin B. Ünlü Ince
Claudia Buntrock
Dirk Lehr
Frank J. Snoek
Gavin Andrews
Gerhard Andersson
Isabella Choi
Jeroen Ruwaard
Jan Philipp Klein
Jill M. Newby
Johanna Schröder
Johannes A.C. Laferton
Kim Van Bastelaar
Kotaro Imamura
Kristofer Vernmark
Leif Boß
Lisa B. Sheeber
Marie Kivi
Matthias Berking
Nickolai Titov
Per Carlbring
Robert Johansson
Robin Kenter
Sarah Perini
Steffen Moritz
Stephanie Nobis
Thomas Berger
Viktor Kaldo
Yvonne Forsell
Nils Lindefors
Martin Kraepelien
Cecilia Björkelund
Norito Kawakami
Pim Cuijpers
Internet-based guided self-help
Psychotherapy
Depression
Meta-analysis
Elsevier
Clinical Psychology Review, 63 (2018) 80-92. doi:10.1016/j.cpr.2018.06.007
journal
Clinical Psychology Review
© 2018 Published by Elsevier Ltd.
0272-7358
63
July 2018
80-92
80
92
10.1016/j.cpr.2018.06.007
https://doi.org/10.1016/j.cpr.2018.06.007
2010-04-23
true
10.1016/j.cpr.2018.06.007
elsevier.com
sciencedirect.com
10.1016/j.cpr.2018.06.007
2010-04-23
true
noindex
elsevier.com
sciencedirect.com
VoR
Elsevier
2020-07-16T15:23:44+02:00
2018-07-02T15:30:49Z
2020-07-16T15:23:44+02:00
True
Internet-based guided self-help; Psychotherapy; Depression; Meta-analysis;
uuid:c8551d9a-aedc-471e-9b32-ab7db44cde86
uuid:924f2de7-d58d-4384-9616-6cf579137fcf
endstream
endobj
4 0 obj
<<
/Dests 16 0 R
/EmbeddedFiles 17 0 R
/JavaScript 18 0 R
>>
endobj
5 0 obj
<<
/Intent [/View /Design]
/Name (Layer 1)
/Type /OCG
/Usage 19 0 R
>>
endobj
6 0 obj
<<
/Annots [20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R 26 0 R 27 0 R 28 0 R 29 0 R
30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R 36 0 R 37 0 R 38 0 R 39 0 R
40 0 R 41 0 R 42 0 R 43 0 R 44 0 R 45 0 R 46 0 R 47 0 R 48 0 R 49 0 R
50 0 R 51 0 R 52 0 R 53 0 R 54 0 R 55 0 R 56 0 R 57 0 R 58 0 R 59 0 R
60 0 R 61 0 R 62 0 R 63 0 R 64 0 R 65 0 R 66 0 R 67 0 R 68 0 R 69 0 R
70 0 R 71 0 R 72 0 R 73 0 R 74 0 R 75 0 R 76 0 R 77 0 R 78 0 R 79 0 R
80 0 R 81 0 R 82 0 R 83 0 R 84 0 R]
/Contents [85 0 R 86 0 R 87 0 R 88 0 R 89 0 R 90 0 R 91 0 R 92 0 R]
/CropBox [0 0 595.276 793.701]
/MediaBox [0 0 595.276 793.701]
/Parent 93 0 R
/QInserted true
/Resources <<
/ColorSpace <<
/CS0 [/Separation /macblue /DeviceCMYK 94 0 R]
>>
/ExtGState <<
/GS0 95 0 R
/GS1 96 0 R
>>
/Font <<
/C0_0 97 0 R
/T1_0 98 0 R
/T1_1 99 0 R
/T1_2 100 0 R
/T1_3 101 0 R
/T1_4 102 0 R
/T1_5 103 0 R
/T1_6 104 0 R
>>
/ProcSet [/PDF /Text /ImageC]
/XObject <<
/Fm0 105 0 R
/Im0 106 0 R
/Im1 107 0 R
>>
>>
/Rotate 0
/Type /Page
>>
endobj
7 0 obj
<<
/Count 22
/First 108 0 R
/Last 108 0 R
>>
endobj
8 0 obj
<<
/P ()
/S /D
/St 80
>>
endobj
9 0 obj
<<
/Count 14
/Kids [93 0 R 109 0 R]
/Type /Pages
>>
endobj
10 0 obj
<<
/Length 3
>>
stream
Q
endstream
endobj
11 0 obj
<<
/Length 3
>>
stream
q
endstream
endobj
13 0 obj
<<
/Differences [24 /breve /caron /circumflex /dotaccent /hungarumlaut /ogonek /ring /tilde 39
/quotesingle 96 /grave 128 /bullet /dagger /daggerdbl /ellipsis /emdash /endash
/florin /fraction /guilsinglleft /guilsinglright /minus /perthousand /quotedblbase /quotedblleft /quotedblright /quoteleft
/quoteright /quotesinglbase /trademark /fi /fl /Lslash /OE /Scaron /Ydieresis /Zcaron
/dotlessi /lslash /oe /scaron /zcaron 160 /Euro 164 /currency 166
/brokenbar 168 /dieresis /copyright /ordfeminine 172 /logicalnot /.notdef /registered /macron
/degree /plusminus /twosuperior /threesuperior /acute /mu 183 /periodcentered /cedilla /onesuperior
/ordmasculine 188 /onequarter /onehalf /threequarters 192 /Agrave /Aacute /Acircumflex /Atilde
/Adieresis /Aring /AE /Ccedilla /Egrave /Eacute /Ecircumflex /Edieresis /Igrave /Iacute
/Icircumflex /Idieresis /Eth /Ntilde /Ograve /Oacute /Ocircumflex /Otilde /Odieresis /multiply
/Oslash /Ugrave /Uacute /Ucircumflex /Udieresis /Yacute /Thorn /germandbls /agrave /aacute
/acircumflex /atilde /adieresis /aring /ae /ccedilla /egrave /eacute /ecircumflex /edieresis
/igrave /iacute /icircumflex /idieresis /eth /ntilde /ograve /oacute /ocircumflex /otilde
/odieresis /divide /oslash /ugrave /uacute /ucircumflex /udieresis /yacute /thorn /ydieresis]
/Type /Encoding
>>
endobj
14 0 obj
<<
/BaseFont /Helvetica
/Encoding 13 0 R
/Name /Helv
/Subtype /Type1
/Type /Font
>>
endobj
15 0 obj
<<
/BaseFont /ZapfDingbats
/Name /ZaDb
/Subtype /Type1
/Type /Font
>>
endobj
16 0 obj
<<
/Kids [110 0 R 111 0 R 112 0 R 113 0 R 114 0 R 115 0 R 116 0 R 117 0 R]
>>
endobj
17 0 obj
<<
>>
endobj
18 0 obj
<<
>>
endobj
19 0 obj
<<
/CreatorInfo <<
/Creator (Adobe Illustrator 19.2)
/Subtype /Artwork
>>
>>
endobj
20 0 obj
<<
/A <<
/S /URI
/URI (http://www.sciencedirect.com/science/journal/02727358)
>>
/Border [0 0 0]
/Rect [322.242 723.798 369.978 731.792]
/Subtype /Link
/Type /Annot
>>
endobj
21 0 obj
<<
/A <<
/S /URI
/URI (https://www.elsevier.com/locate/clinpsychrev)
>>
/Border [0 0 0]
/Rect [260.334 668.012 419.074 676.006]
/Subtype /Link
/Type /Annot
>>
endobj
22 0 obj
<<
/A <<
/S /URI
/URI (https://doi.org/10.1016/j.cpr.2018.06.007)
>>
/Border [0 0 0]
/Rect [37.587 730.091 37.587 742.053]
/Subtype /Link
/Type /Annot
>>
endobj
23 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [112.422 580.819 116.447 591.364]
/Subtype /Link
/Type /Annot
>>
endobj
24 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [118.658 581.896 122.627 592.498]
/Subtype /Link
/Type /Annot
>>
endobj
25 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [124.838 580.819 129.26 591.364]
/Subtype /Link
/Type /Annot
>>
endobj
26 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [225.411 580.819 229.776 591.364]
/Subtype /Link
/Type /Annot
>>
endobj
27 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [231.987 580.819 236.466 591.364]
/Subtype /Link
/Type /Annot
>>
endobj
28 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [306.822 580.819 310.507 591.364]
/Subtype /Link
/Type /Annot
>>
endobj
29 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [378.255 580.819 382.28 591.364]
/Subtype /Link
/Type /Annot
>>
endobj
30 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [435.005 580.819 442.715 591.364]
/Subtype /Link
/Type /Annot
>>
endobj
31 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [107.093 567.836 111.118 578.438]
/Subtype /Link
/Type /Annot
>>
endobj
32 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [209.31 567.836 213.732 578.438]
/Subtype /Link
/Type /Annot
>>
endobj
33 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [216 567.836 224.39 578.438]
/Subtype /Link
/Type /Annot
>>
endobj
34 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [291.061 567.836 294.916 578.438]
/Subtype /Link
/Type /Annot
>>
endobj
35 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [392.088 567.836 394.696 578.438]
/Subtype /Link
/Type /Annot
>>
endobj
36 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [135.269 554.91 139.691 565.455]
/Subtype /Link
/Type /Annot
>>
endobj
37 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [215.093 554.91 219.231 565.455]
/Subtype /Link
/Type /Annot
>>
endobj
38 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [335.509 554.91 339.534 565.455]
/Subtype /Link
/Type /Annot
>>
endobj
39 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [416.523 554.91 420.548 565.455]
/Subtype /Link
/Type /Annot
>>
endobj
40 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [95.811 541.927 100.346 552.529]
/Subtype /Link
/Type /Annot
>>
endobj
41 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [102.557 541.927 109.191 552.529]
/Subtype /Link
/Type /Annot
>>
endobj
42 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [208.403 541.927 210.784 552.529]
/Subtype /Link
/Type /Annot
>>
endobj
43 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [298.885 541.927 303.25 552.529]
/Subtype /Link
/Type /Annot
>>
endobj
44 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [354.557 541.927 356.882 552.529]
/Subtype /Link
/Type /Annot
>>
endobj
45 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [433.361 541.927 437.612 552.529]
/Subtype /Link
/Type /Annot
>>
endobj
46 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [109.474 529.001 111.798 539.546]
/Subtype /Link
/Type /Annot
>>
endobj
47 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [208.46 529.001 215.206 539.546]
/Subtype /Link
/Type /Annot
>>
endobj
48 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [282.557 529.001 287.036 539.546]
/Subtype /Link
/Type /Annot
>>
endobj
49 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [370.375 529.001 374.4 539.546]
/Subtype /Link
/Type /Annot
>>
endobj
50 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [462.16 529.001 466.469 539.546]
/Subtype /Link
/Type /Annot
>>
endobj
51 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [103.975 516.019 108.397 526.62]
/Subtype /Link
/Type /Annot
>>
endobj
52 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [110.608 516.019 118.772 526.62]
/Subtype /Link
/Type /Annot
>>
endobj
53 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [121.039 516.019 129.6 526.62]
/Subtype /Link
/Type /Annot
>>
endobj
54 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [220.876 516.019 225.184 526.62]
/Subtype /Link
/Type /Annot
>>
endobj
55 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [227.395 516.019 235.672 526.62]
/Subtype /Link
/Type /Annot
>>
endobj
56 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [351.553 516.019 355.918 526.62]
/Subtype /Link
/Type /Annot
>>
endobj
57 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [449.518 516.019 452.636 526.62]
/Subtype /Link
/Type /Annot
>>
endobj
58 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [114.746 503.093 117.921 513.638]
/Subtype /Link
/Type /Annot
>>
endobj
59 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [214.753 503.093 217.417 513.638]
/Subtype /Link
/Type /Annot
>>
endobj
60 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [263.622 503.093 265.946 513.638]
/Subtype /Link
/Type /Annot
>>
endobj
61 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [344.239 503.093 348.775 513.638]
/Subtype /Link
/Type /Annot
>>
endobj
62 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [404.617 503.093 408.813 513.638]
/Subtype /Link
/Type /Annot
>>
endobj
63 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [117.865 490.167 122.23 500.712]
/Subtype /Link
/Type /Annot
>>
endobj
64 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [195.534 490.167 201.713 500.712]
/Subtype /Link
/Type /Annot
>>
endobj
65 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [271.105 490.167 277.568 500.712]
/Subtype /Link
/Type /Annot
>>
endobj
66 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [279.779 490.167 286.129 500.712]
/Subtype /Link
/Type /Annot
>>
endobj
67 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [375.874 490.167 379.899 500.712]
/Subtype /Link
/Type /Annot
>>
endobj
68 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [448.384 490.167 452.579 500.712]
/Subtype /Link
/Type /Annot
>>
endobj
69 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [95.414 477.184 103.294 487.729]
/Subtype /Link
/Type /Annot
>>
endobj
70 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [176.428 477.184 180.453 487.729]
/Subtype /Link
/Type /Annot
>>
endobj
71 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [263.055 477.184 266.683 487.729]
/Subtype /Link
/Type /Annot
>>
endobj
72 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [343.899 477.184 352.006 487.729]
/Subtype /Link
/Type /Annot
>>
endobj
73 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [418.28 477.184 426.671 487.729]
/Subtype /Link
/Type /Annot
>>
endobj
74 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [428.882 477.184 435.288 487.729]
/Subtype /Link
/Type /Annot
>>
endobj
75 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [107.093 464.258 115.483 474.803]
/Subtype /Link
/Type /Annot
>>
endobj
76 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [186.35 464.258 194.797 474.803]
/Subtype /Link
/Type /Annot
>>
endobj
77 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [285.562 464.258 293.953 474.803]
/Subtype /Link
/Type /Annot
>>
endobj
78 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [386.079 464.258 394.583 474.803]
/Subtype /Link
/Type /Annot
>>
endobj
79 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [482.797 464.258 485.972 474.803]
/Subtype /Link
/Type /Annot
>>
endobj
80 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [97.739 451.276 101.764 461.82]
/Subtype /Link
/Type /Annot
>>
endobj
81 0 obj
<<
/A <<
/S /URI
/URI (https://doi.org/10.1016/j.cpr.2018.06.007)
>>
/Border [0 0 0]
/Rect [37.587 72.737 159.874 79.143]
/Subtype /Link
/Type /Annot
>>
endobj
82 0 obj
<<
/A <<
/S /URI
/URI (mailto:e.karyotaki@vu.nl)
>>
/Border [0 0 0]
/Rect [92.126 97.852 144.057 104.202]
/Subtype /Link
/Type /Annot
>>
endobj
83 0 obj
<<
/A 118 0 R
/BS <<
/S /S
/Type /Border
/W 0
>>
/Border [0 0 0]
/Rect [229.379 748.324 377.065 759.864]
/Subtype /Link
/Type /Annot
>>
endobj
84 0 obj
<<
/A 119 0 R
/BS <<
/S /S
/Type /Border
/W 0
>>
/Border [0 0 0]
/Rect [501.568 608.368 531.104 622.792]
/Subtype /Link
/Type /Annot
>>
endobj
85 0 obj
<<
/Length 1059
/Filter /FlateDecode
>>
stream
HVMs6WHD襓Di[,æHR,[5xx킌Z{]e_Yu PhmFQV&n2F1R:K(K!^ZYj((9©&2rrsRPw\g̛"-oF,n2Ca|8;[41\Q+'u%Խn2RRK*tJ0jH^lPו;n'->eHOm+kd [,.<'N=,6GCiF;ESrDV:E1=MլD~.!d*(K
RGuNt]=YM?Jt(U