%PDF-1.3
%
1 0 obj
<<
/Metadata 2 0 R
/Names 3 0 R
/Outlines 4 0 R
/PageLabels 5 0 R
/Pages 6 0 R
/Threads [7 0 R]
/Type /Catalog
>>
endobj
8 0 obj
<<
/CreationDate (D:20121021125100+08'00')
/Creator (Arbortext Advanced Print Publisher 9.1.440/W Unicode)
/ModDate (D:20121021125401+08'00')
/Producer (Acrobat Distiller 10.0.0 \(Windows\))
/Title (Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner)
>>
endobj
2 0 obj
<<
/Length 3224
/Subtype /XML
/Type /Metadata
>>
stream
BMC Genomics 2012, 13:1. doi:10.1186/1471-2164-13-411
application/pdf
http://dx.doi.org/10.1186/1471-2164-13-411
Tatiana Nedelko
Heike Kollmus
Frank Klawonn
Sabine Spijker
Lu Lu
Manuela He�man
Rudi Alberts
Robert W. Williams
Klaus Schughart
Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner
BMC Genomics 2012, 13:1. doi:10.1186/1471-2164-13-411
BMC Genomics
2012-08-20
� 2012 Nedelko et al.; licensee BioMed Central Ltd.
True
BMC Genomics
10.1186/1471-2164-13-411
1
1
1
� 2012 Nedelko et al.; licensee BioMed Central Ltd.
BMC Genomics
journal
13
reprints@biomedcentral.com
2012-08-20
1
1
BMC Genomics
endstream
endobj
3 0 obj
<<
/Dests 9 0 R
/EmbeddedFiles 10 0 R
>>
endobj
4 0 obj
<<
/Count 13
/First 11 0 R
/Last 12 0 R
>>
endobj
5 0 obj
<<
/Nums [0 13 0 R 1 14 0 R]
>>
endobj
6 0 obj
<<
/Count 20
/Kids [15 0 R 16 0 R]
/Type /Pages
>>
endobj
7 0 obj
<<
/F 17 0 R
/I 18 0 R
>>
endobj
9 0 obj
<<
/Kids [19 0 R 20 0 R]
>>
endobj
10 0 obj
<<
/Kids [21 0 R]
>>
endobj
11 0 obj
<<
/Count -3
/Dest
/First 22 0 R
/Last 23 0 R
/Next 24 0 R
/Parent 4 0 R
/Title
>>
endobj
12 0 obj
<<
/Dest
/Parent 4 0 R
/Prev 25 0 R
/Title
>>
endobj
13 0 obj
<<
/P (0)
>>
endobj
14 0 obj
<<
/S /D
>>
endobj
15 0 obj
<<
/Count 11
/Kids [26 0 R 27 0 R 28 0 R 29 0 R 30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R
36 0 R]
/Parent 6 0 R
/Type /Pages
>>
endobj
16 0 obj
<<
/Count 9
/Kids [37 0 R 38 0 R 39 0 R 40 0 R 41 0 R 42 0 R 43 0 R 44 0 R 45 0 R]
/Parent 6 0 R
/Type /Pages
>>
endobj
17 0 obj
<<
/N 46 0 R
/P 27 0 R
/R [54 684 541 707]
/T 7 0 R
/V 47 0 R
>>
endobj
18 0 obj
<<
/Title
>>
endobj
19 0 obj
<<
/Limits [ ]
/Names [ 48 0 R 49 0 R 49 0 R 49 0 R 49 0 R
49 0 R 49 0 R 49 0 R 49 0 R 49 0 R
49 0 R 48 0 R 49 0 R 49 0 R 49 0 R
49 0 R 49 0 R 49 0 R 49 0 R 49 0 R
49 0 R 49 0 R 48 0 R 49 0 R 49 0 R
49 0 R 49 0 R 49 0 R 49 0 R 49 0 R
49 0 R 49 0 R 49 0 R 48 0 R 49 0 R
49 0 R 49 0 R 49 0 R 49 0 R 50 0 R
50 0 R 50 0 R 50 0 R 50 0 R 49 0 R
50 0 R 50 0 R 50 0 R 50 0 R 50 0 R
50 0 R 50 0 R 50 0 R 50 0 R 50 0 R
49 0 R 50 0 R 50 0 R 50 0 R 50 0 R
50 0 R 50 0 R 50 0 R 50 0 R]
>>
endobj
20 0 obj
<<
/Limits [ ]
/Names [ 50 0 R 50 0 R 49 0 R 50 0 R 50 0 R
50 0 R 50 0 R 49 0 R 49 0 R 51 0 R
52 0 R 53 0 R 54 0 R 55 0 R 56 0 R
57 0 R 58 0 R 59 0 R 60 0 R 61 0 R
62 0 R 63 0 R 64 0 R 65 0 R 66 0 R
67 0 R 68 0 R 69 0 R 69 0 R 70 0 R
69 0 R 71 0 R 72 0 R 73 0 R 74 0 R
75 0 R 76 0 R 75 0 R 77 0 R 78 0 R
79 0 R 80 0 R 81 0 R 82 0 R 83 0 R
84 0 R 85 0 R 86 0 R 86 0 R 86 0 R
86 0 R 86 0 R 87 0 R]
>>
endobj
21 0 obj
<<
/Limits [ ]
/Names [ 88 0 R]
>>
endobj
22 0 obj
<<
/Dest
/Next 89 0 R
/Parent 11 0 R
/Title
>>
endobj
23 0 obj
<<
/Dest
/Parent 11 0 R
/Prev 89 0 R
/Title
>>
endobj
24 0 obj
<<
/Dest
/Next 90 0 R
/Parent 4 0 R
/Prev 11 0 R
/Title
>>
endobj
25 0 obj
<<
/Dest
/Next 12 0 R
/Parent 4 0 R
/Prev 91 0 R
/Title
>>
endobj
26 0 obj
<<
/Contents 92 0 R
/Type /Page
/Resources <<
/Font <<
/F1 93 0 R
/F2 94 0 R
/F3 95 0 R
/F4 96 0 R
/F5 97 0 R
>>
/XObject <<
/Xf1 98 0 R
>>
>>
/Annots [99 0 R 100 0 R 101 0 R]
/Parent 15 0 R
/MediaBox [0 0 595 842]
>>
endobj
27 0 obj
<<
/Annots [102 0 R 103 0 R 104 0 R 105 0 R 106 0 R 107 0 R 108 0 R 109 0 R 110 0 R 111 0 R
112 0 R]
/B [17 0 R 46 0 R 113 0 R 114 0 R 115 0 R 116 0 R]
/Contents [117 0 R 118 0 R 119 0 R 120 0 R 121 0 R 122 0 R 123 0 R 124 0 R]
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 125 0 R
/Rotate 0
/Thumb 126 0 R
/Type /Page
>>
endobj
28 0 obj
<<
/Annots [127 0 R 128 0 R 129 0 R 130 0 R 131 0 R 132 0 R 133 0 R 134 0 R 135 0 R 136 0 R
137 0 R 138 0 R 139 0 R 140 0 R 141 0 R 142 0 R 143 0 R 144 0 R 145 0 R 146 0 R
147 0 R 148 0 R 149 0 R 150 0 R 151 0 R 152 0 R 153 0 R 154 0 R 155 0 R 156 0 R]
/B [157 0 R 158 0 R]
/Contents 159 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 160 0 R
/Rotate 0
/Thumb 161 0 R
/Type /Page
>>
endobj
29 0 obj
<<
/Annots [162 0 R 163 0 R]
/B [164 0 R 165 0 R]
/Contents 166 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 167 0 R
/Rotate 0
/Thumb 168 0 R
/Type /Page
>>
endobj
30 0 obj
<<
/Annots [169 0 R 170 0 R 171 0 R 172 0 R 173 0 R 174 0 R 175 0 R 176 0 R 177 0 R 178 0 R
179 0 R 180 0 R 181 0 R 182 0 R 183 0 R 184 0 R 185 0 R 186 0 R 187 0 R 188 0 R
189 0 R 190 0 R 191 0 R 192 0 R]
/B [193 0 R 194 0 R]
/Contents 195 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 196 0 R
/Rotate 0
/Thumb 197 0 R
/Type /Page
>>
endobj
31 0 obj
<<
/Annots [198 0 R 199 0 R 200 0 R 201 0 R 202 0 R]
/B [203 0 R 204 0 R]
/Contents 205 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 206 0 R
/Rotate 0
/Thumb 207 0 R
/Type /Page
>>
endobj
32 0 obj
<<
/Annots [208 0 R 209 0 R 210 0 R 211 0 R 212 0 R 213 0 R 214 0 R 215 0 R]
/B [216 0 R 217 0 R]
/Contents 218 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 219 0 R
/Rotate 0
/Thumb 220 0 R
/Type /Page
>>
endobj
33 0 obj
<<
/Contents 221 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 222 0 R
/Rotate 0
/Thumb 223 0 R
/Type /Page
>>
endobj
34 0 obj
<<
/Contents 224 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 225 0 R
/Rotate 0
/Thumb 226 0 R
/Type /Page
>>
endobj
35 0 obj
<<
/Annots [227 0 R 228 0 R 229 0 R 230 0 R 231 0 R 232 0 R 233 0 R 234 0 R]
/B [235 0 R 236 0 R]
/Contents 237 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 238 0 R
/Rotate 0
/Thumb 239 0 R
/Type /Page
>>
endobj
36 0 obj
<<
/Contents 240 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 15 0 R
/Resources 241 0 R
/Rotate 0
/Thumb 242 0 R
/Type /Page
>>
endobj
37 0 obj
<<
/Annots [243 0 R 244 0 R 245 0 R 246 0 R 247 0 R 248 0 R 249 0 R 250 0 R 251 0 R 252 0 R]
/B [253 0 R 254 0 R]
/Contents 255 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 256 0 R
/Rotate 0
/Thumb 257 0 R
/Type /Page
>>
endobj
38 0 obj
<<
/Annots [258 0 R 259 0 R 260 0 R 261 0 R 262 0 R 263 0 R 264 0 R 265 0 R 266 0 R 267 0 R
268 0 R 269 0 R 270 0 R 271 0 R 272 0 R]
/B [273 0 R 274 0 R]
/Contents 275 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 276 0 R
/Rotate 0
/Thumb 277 0 R
/Type /Page
>>
endobj
39 0 obj
<<
/Contents 278 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 279 0 R
/Rotate 0
/Thumb 280 0 R
/Type /Page
>>
endobj
40 0 obj
<<
/Contents 281 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 282 0 R
/Rotate 0
/Thumb 283 0 R
/Type /Page
>>
endobj
41 0 obj
<<
/Annots [284 0 R 285 0 R 286 0 R 287 0 R 288 0 R 289 0 R 290 0 R 291 0 R 292 0 R 293 0 R
294 0 R 295 0 R 296 0 R 297 0 R]
/B [298 0 R 299 0 R]
/Contents 300 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 301 0 R
/Rotate 0
/Thumb 302 0 R
/Type /Page
>>
endobj
42 0 obj
<<
/Annots [303 0 R 304 0 R 305 0 R 306 0 R 307 0 R 308 0 R 309 0 R 310 0 R 311 0 R 312 0 R
313 0 R 314 0 R 315 0 R 316 0 R 317 0 R 318 0 R 319 0 R 320 0 R 321 0 R 322 0 R]
/B [323 0 R 324 0 R]
/Contents 325 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 326 0 R
/Rotate 0
/Thumb 327 0 R
/Type /Page
>>
endobj
43 0 obj
<<
/Annots [328 0 R 329 0 R 330 0 R 331 0 R 332 0 R 333 0 R 334 0 R 335 0 R 336 0 R 337 0 R]
/B [338 0 R 339 0 R 340 0 R]
/Contents 341 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 342 0 R
/Rotate 0
/Thumb 343 0 R
/Type /Page
>>
endobj
44 0 obj
<<
/B [344 0 R 345 0 R 346 0 R 347 0 R]
/Contents 348 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 349 0 R
/Rotate 0
/Thumb 350 0 R
/Type /Page
>>
endobj
45 0 obj
<<
/Annots [351 0 R 352 0 R]
/B [353 0 R 354 0 R 355 0 R 47 0 R]
/Contents 356 0 R
/CropBox [0 0 595.2760009766 793.7009887695]
/MediaBox [0 0 595.2760009766 793.7009887695]
/Parent 16 0 R
/Resources 357 0 R
/Rotate 0
/Thumb 358 0 R
/Type /Page
>>
endobj
46 0 obj
<<
/N 113 0 R
/P 27 0 R
/R [54 557 541 707]
/T 7 0 R
/V 17 0 R
>>
endobj
47 0 obj
<<
/N 17 0 R
/P 45 0 R
/R [302 58 541 76]
/T 7 0 R
/V 355 0 R
>>
endobj
48 0 obj
<<
/D [43 0 R /FitR 0 794 596 0]
>>
endobj
49 0 obj
<<
/D [44 0 R /FitR 0 794 596 0]
>>
endobj
50 0 obj
<<
/D [45 0 R /FitR 0 794 596 0]
>>
endobj
51 0 obj
<<
/D [29 0 R /FitR 0 794 596 0]
>>
endobj
52 0 obj
<<
/D [30 0 R /FitR 0 794 596 0]
>>
endobj
53 0 obj
<<
/D [31 0 R /FitR 0 794 596 0]
>>
endobj
54 0 obj
<<
/D [32 0 R /FitR 0 794 596 0]
>>
endobj
55 0 obj
<<
/D [33 0 R /FitR 0 794 596 0]
>>
endobj
56 0 obj
<<
/D [34 0 R /FitR 0 794 596 0]
>>
endobj
57 0 obj
<<
/D [35 0 R /FitR 0 794 596 0]
>>
endobj
58 0 obj
<<
/D [37 0 R /FitR 0 794 596 0]
>>
endobj
59 0 obj
<<
/D [43 0 R /FitR 0 636 596 636]
>>
endobj
60 0 obj
<<
/D [43 0 R /FitR 0 606 596 606]
>>
endobj
61 0 obj
<<
/D [43 0 R /FitR 0 531 596 531]
>>
endobj
62 0 obj
<<
/D [43 0 R /FitR 0 492 596 492]
>>
endobj
63 0 obj
<<
/D [43 0 R /FitR 0 435 596 435]
>>
endobj
64 0 obj
<<
/D [43 0 R /FitR 0 342 596 342]
>>
endobj
65 0 obj
<<
/D [43 0 R /FitR 0 294 596 294]
>>
endobj
66 0 obj
<<
/D [43 0 R /FitR 0 264 596 264]
>>
endobj
67 0 obj
<<
/D [38 0 R /FitR 0 794 596 0]
>>
endobj
68 0 obj
<<
/D [39 0 R /FitR 0 794 596 0]
>>
endobj
69 0 obj
<<
/D [27 0 R /FitR 0 794 596 794]
>>
endobj
70 0 obj
<<
/D [27 0 R /FitR 0 333 596 333]
>>
endobj
71 0 obj
<<
/D [43 0 R /FitR 0 167 596 167]
>>
endobj
72 0 obj
<<
/D [27 0 R /FitR 0 266 596 266]
>>
endobj
73 0 obj
<<
/D [41 0 R /FitR 0 242 596 242]
>>
endobj
74 0 obj
<<
/D [41 0 R /FitR 0 230 596 230]
>>
endobj
75 0 obj
<<
/D [42 0 R /FitR 0 794 596 794]
>>
endobj
76 0 obj
<<
/D [42 0 R /FitR 0 298 596 298]
>>
endobj
77 0 obj
<<
/D [42 0 R /FitR 0 361 596 361]
>>
endobj
78 0 obj
<<
/D [28 0 R /FitR 0 205 596 205]
>>
endobj
79 0 obj
<<
/D [28 0 R /FitR 0 193 596 193]
>>
endobj
80 0 obj
<<
/D [29 0 R /FitR 0 145 596 145]
>>
endobj
81 0 obj
<<
/D [30 0 R /FitR 0 794 596 794]
>>
endobj
82 0 obj
<<
/D [30 0 R /FitR 0 205 596 205]
>>
endobj
83 0 obj
<<
/D [31 0 R /FitR 0 229 596 229]
>>
endobj
84 0 obj
<<
/D [32 0 R /FitR 0 97 596 97]
>>
endobj
85 0 obj
<<
/D [41 0 R /FitR 0 794 596 794]
>>
endobj
86 0 obj
<<
/D [43 0 R /FitR 0 794 596 794]
>>
endobj
87 0 obj
<<
/D [43 0 R /FitR 0 320 596 320]
>>
endobj
88 0 obj
<<
/EF 359 0 R
/F (folder.joboptions)
/Type /Filespec
/UF
>>
endobj
89 0 obj
<<
/Dest
/Next 23 0 R
/Parent 11 0 R
/Prev 22 0 R
/Title
>>
endobj
90 0 obj
<<
/Count -5
/Dest
/First 360 0 R
/Last 361 0 R
/Next 362 0 R
/Parent 4 0 R
/Prev 24 0 R
/Title
>>
endobj
91 0 obj
<<
/Dest
/Next 25 0 R
/Parent 4 0 R
/Prev 363 0 R
/Title
>>
endobj
92 0 obj
<<
/Length 1328
/Filter /FlateDecode
>>
stream
xW[OFC<tz:NzNMb@rG{
DtCgc@(曙of֓#hGvZм09jcۨC`FrS|5sZFA% FZKE4N.ϣG?p.p_ih/QL',tӐ].,(,x@Dc
5
v"6,Zb !5h9f{tEC NҨځVFʁkQU5%``<0T
8*hfpQƗ;)}R`*4|D
JO:"6>CZĞ?GC07'F"Z~bTmޜgK [/j0"HAq$1kHv]'Siu kCC$ufWǏ9,C$E>*qyUh.R:B@J\3.2J0p__U:_
+O-Vx'kl;NXj:U(LqSI[{@q
xmy)j'.݉ͮk,|(,(2IOM_zK"6_$edg@[^+r\*S@1g78nssKr9[)>1&bYW'/NUϕ㈙2,0qlIK,&$-ip`b"Iίw˼*%2
'_gΖ-Le
.v}j~Aa)pneN